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To receive a diagnosis of DRESS syndrome, a person must meet the hospitalization acute rash a reaction that is likely drug-related In addition, three out of the four issues below should be present: fever higher than 38°C enlarged lymph nodes in at least two sites involvement of at least one internal organ blood count abnormalities Researchers in Japan have suggested a different set of criteria, which are similar but include the presence of HHV6 reactivation

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